Where Data Meets Computer Science
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Cell Protrusions

Identification, description and quantification of the cell behavior observed by time-lapse confocal microscopy

Research, development and implementation of novel 4D image analysis and processing methods for identification, description and quantification of the cell behavior (protrusion, adhesion and invasion), as observed by time-lapse confocal microscopy.

An image of a cell with detected protrusions (blue stars).

An image of a cell with detected protrusions (blue stars).

 

Collaborators:

  • Dr Maddy Parsons, Randall Division of Cell and Molecular Biophysics, King’s College London, UK

Publications:

  • [2013,article] bibtex
    T. M. E. Scales, B. Obara, M. R. Holt, N. A. Hotchin, F. Berditchevski, and M. Parsons, "$\alpha$3$\beta$1 integrins regulate CD151 complex assembly and membrane dynamics of carcinoma cells within 3D environments," Oncogene, vol. 32, iss. 34, pp. 3965-3979, 2013.
    @article{Scales2013,
      author = {Timothy M.E. Scales and Boguslaw Obara and Mark R. Holt and Neil A. Hotchin and Fedor Berditchevski and Maddy Parsons},
      title = {$\alpha$3$\beta$1 integrins regulate {CD151} complex assembly and membrane dynamics of carcinoma cells within {3D} environments},
      journal = {Oncogene},
      volume = {32},
      number = {34},
      pages = {3965-3979},
      year = {2013}
    }