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Colocalisation

An image processing approach for colocalization analysis of objects in dual-color confocal images

The colocalization technique is important to many cell biological and physiological studies during the demonstration of a relationship between pairs of bio-molecules.

3D colocalized spots.

Collaborators:

  • Dr Philippe Laissue, Department of Biological Sciences, University of Essex, UK
  • Dr Martin Goldberg, School of Biological & Biomedical Sciences, University of Durham, UK
  • Dr Tim Hawkins, Microscopy & Bioimaging, University of Durham, UK
  • Prof. Patrick J. Hussey, School of Biological & Biomedical Sciences, University of Durham, UK
  • Prof. Roy Quinlan, School of Biological & Biomedical Sciences, University of Durham, UK

Publications:

  • [2013,article] bibtex
    B. Obara, A. Jabeen, N. Fernandez, and P. P. Laissue, "A novel method for quantified, superresolved, three-dimensional colocalisation of isotropic, fluorescent particles," Histochemistry and Cell Biology, vol. 139, iss. 3, pp. 391-402, 2013.
    @article{Obara2013a,
      author = {Boguslaw Obara and Asma Jabeen and Nelson Fernandez and Pierre Philippe Laissue},
      title = {A novel method for quantified, superresolved, three-dimensional colocalisation of isotropic, fluorescent particles},
      journal = {Histochemistry and Cell Biology},
      volume = {139},
      number = {3},
      pages = {391-402},
      year = {2013}
    }
  • [2013,inproceedings] bibtex
    B. Obara, R. Alghamdi, A. Jabeen, N. Fernandez, K. South, P. J. Reeves, and P. P. Laissue, "Quantified, three-dimensional, object-based colocalisation for characterising cellular phenotypes," in Focus on Microscopy, Maastricht, The Netherlands, 2013.
    @inproceedings{Obara2013b,
      author = {Boguslaw Obara and Rana Alghamdi and Asma Jabeen and Nelson Fernandez and Kieron South and Philip J Reeves and Pierre Philippe Laissue},
      title = {Quantified, three-dimensional, object-based colocalisation for characterising cellular phenotypes},
      booktitle = {Focus on Microscopy},
      address = {Maastricht, The Netherlands},
      month = {24-27 March},
      year = {2013}
    }